This volume provides readers with a historical foundation in standard techniques and a comprehensive update on the latest methods used in making gene-modified m

Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularlyfor gener

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeuti

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,conti

The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models pri