Randomized controlled trials are one of the most powerful and revolutionary tools of research. This book is a convenient and accessible description of the under

Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical

Bradford Hill has defined a clinical trial as "A carefully and ethically designed experiment with the aim of answering some precisely framed question" [1]. This

The contributors to this study present a balanced view of the strengths and weaknesses of randomised controlled trials in the medical setting. They cover all th

Health and human services currently face a series of challenges – such as aging populations, chronic diseases and new endemics – that require highly complex