Immunotherapy of Cancer with Sensitized T Lymphocytes

Download or read book Immunotherapy of Cancer with Sensitized T Lymphocytes written by Alfred E. Chang and published by R. G. Landes. This book was released on 1994 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a review of the field of cellular immunotherapy utilizing sensitized T lymphocytes. The contributors are experts in the field of experimental and clinical immunotherapy. Cellular therapy of malignancy has become more feasible with an increased understanding of the interactions between immune cells and tumours. The text reviews the mechanisms of T cell activation critical for the induction of antitumour reactivity and the problems associated with tumour-induced immunosuppression. It goes on to describe the functional properties of sensitized Y lymphocytes with regard to cytokine secretion, in vivo trafficking, and their therapeutic effectiveness. Strategies and methods for the immunological approach to cancer treatment are also examined.